Several neurochemical changes besides an accumulation of amyloid occur in the brain in individuals with Alzheimer disease. Researchers at IND are developing multiple imaging ligands to better understand the changes occurring in the brain in Alzheimer disease. Imaging ligands to detect changes in the norepinepherine system and neuroinflammation are critical to the development of future medications.
PPMI Pre-Motor Arm
The pre-motor arm of PPMI will enroll participants who do not have Parkinson’s disease and are living with one of three potential risk factors for PD.
If you do not have a diagnosis of Parkinson disease and are 60 years of age or older you can participate in the hyposmic (smell testing) arm of the study by going to: michaeljfox.org/takethesmellsurvery or by contacting the call center (877) 525 PPMI. For more information go to the press release by clicking here.
Research at IND
At IND the clinical research team is committed to improving current treatments, diagnostic tools and ultimately developing strategies to slow progression and even prevent the onset of neurodegenerative conditions.
A major focus of the research program at IND is to develop tools (biomarkers) to improve the diagnosis of neurologic conditions and effectively measure progression of disease. Brain imaging has proven to be one of the most useful biomarkers for neurologic conditions. Over the years we have realized the key role of biomarkers in understanding the changes occurring in the brain. Biomarker development promises to provide the critical tools with the capacity to accelerate research in neurodegenerative disease as well as objectively monitor the effect of new medications.
To learn more about our research on specific diseases, filter the results below based on category.